Thioredoxin, the Ring Master of TCA Circus in Plant Mitochondria

Yes, we are talking about the tricarboxylic acid (TCA) cycle that is also known as Kreb's Cycle or citric acid cycle. You may be aware, this fundamental metabolic pathway is a sequence of enzymatic reactions in which the two carbon atoms of acetyl-CoA are oxidized to carbon dioxide. The overall reactions are complete oxidation of one molecule of acetyl-CoA, the production of two molecules of carbon dioxide, the reduction of of three molecules of NAD+ and one of FAD, and the phosphorylation of one molecule of GDP.